- Gene Regulatory Regions Required for beta Defensin-2 Up-Regulation by Interleukin-1alpha in the Human Middle Ear Epithelial Cell Line
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Kim HJ, Bae JH, Choung YH, Park K, Moon SK
- KMID: 1597332
- Korean J Otolaryngol-Head Neck Surg.
- 2005 May;48(5):577-581.
BACKGROUND AND OBJECTIVES: Innate immunity is important in the middle ear because of the lack of immune cells in the region. Among innate immunities beta-defensin-2 is known to play an... -
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- Molecular Characterization of the NF2 Gene in Korean Patients with Neurofibromatosis Type 2: A Report of Four Novel Mutations
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Seong MW, Yeo IK, Cho SI, Park CK, Kim SK, Paek SH, Kim DG, Jung HW, Park H, Kim SY, Kim JY, Park SS
- KMID: 1096807
- Korean J Lab Med.
- 2010 Apr;30(2):190-194.
- doi: 10.3343/kjlm.2010.30.2.190
BACKGROUND: Neurofibromatosis type 2 (NF2) is an autosomal dominant syndrome caused by the NF2 tumor suppressor gene. However, the NF2 mutation characteristics in Korean patients are not sufficiently understood. In... -
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- Interleukin-6 polymorphism in Korean Obese and Type 2 Diabetic Subjects
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Kim JT, Choi SJ, Lee MK, Park AJ, Oh YS, Shin SH
- KMID: 2177847
- J Korean Diabetes Assoc.
- 2001 Oct;25(5):337-342.
BACKGROUND: Interleukin (IL)-6 is produced by many different cell types, including adipose tissue, and the release is greater in obese subjects. Recently, it has been reported that polymorphism in the... -
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- Conservation of Mucous Epithelial Characteristics in the Human Middle Ear Epithelial Cell Line
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Moon SK, Lee J, Choung YH, Park K, Lim DJ
- KMID: 2276131
- Korean J Otolaryngol-Head Neck Surg.
- 2004 Apr;47(4):299-303.
BACKGROUND AND OBJECTIVES: The stable cell line system of middle ear epithelial cells is essential for studying molecular pathogenesis of otitis media. Recently, we succeeded in establishing the human middle... -
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- The role of tonicity responsive enhancer sites in the transcriptional regulation of human hsp70-2 in response to hypertonic stress
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Heo JI, Lee MS, Kim JH, Lee JS, Kim J, Park JB, Lee JY, Han JA, Kim JI
- KMID: 1094155
- Exp Mol Med.
- 2006 Jun;38(3):295-301.
The inducible 70 kDa heat shock proteins (Hsp70) in mice are encoded by two almost identical genes, hsp70.1 and hsp70.3. Studies have found that only hsp70.1 is induced by hypertonic... -
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- Polymorphisms of tumor necrosis factor-alpha promotor gene in Kawasaki disease and relation to the risk of coronary artery lesion
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Kim SH, Yun JW, Lee YH, Cheon EJ
- KMID: 2281749
- Korean J Pediatr.
- 2009 Apr;52(4):476-480.
- doi: 10.3345/kjp.2009.52.4.476
PURPOSE: The purpose of this study was to investigate the polymorphisms of the TNF-alpha promotor gene, its susceptibility to Kawasaki disease (KD) and to assess whether the TNF-alpha promotor gene... -
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