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Is the Expression of Androgen Receptor Protein Associated With the Length of AC Repeats in the Type III 5-alpha Reductase Gene in Prostate Cancer Patients?

Park JM, Song KH, Lim JS, Kim JW, Sul CK

  • KMID: 2316020
  • Korean J Urol.
  • 2013 Jun;54(6):404-408.
PURPOSE: Type III 5-alpha reductase (SRD5A3; steroid 5-alpha reductase 3) may be associated with the progression of prostate cancer (PCa). The aim of our study was to determine whether the...
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The Effect of Finasteride on Microvessel Density and Expression of Vascular Endothelial Growth Factor and 5alpha-Reductase in Prostatic Hyperplasia

Hyun JH, Cho KH, Han DS, Kim JB, Chang YS

  • KMID: 2314789
  • Korean J Urol.
  • 2009 Oct;50(10):947-954.
PURPOSE: Vascular endothelial growth factor (VEGF), a potent stimulator of angiogenesis and microvessel density (MVD), which is an important indicator of neoangiogenesis, were independently evaluated to elucidate the mechanism of...
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The association of 5-alpha reductase type 2 (SRD5A2) gene polymorphisms with prostate cancer in a Korean population

Choi SY, Kim HJ, Cheong HS, Myung SC

PURPOSE: Steroid 5-alpha reductase type 2 (SRD5A2) modifies testosterone to dihydrotestosterone (DHT) in the prostate. Single-nucleotide polymorphisms (SNPs) of the SRD5A2 gene might affect DHT. We sought to understand the...
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