- 14-3-3ζ Overexpression is Associated with Poor Prognosis in Ovarian Cancer
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Kim HJ, Sung SH, Kim CY, Bae MK, Cho MS, Kim YH, Kim SC, Ju W
- KMID: 2418848
- Yonsei Med J.
- 2018 Jan;59(1):51-56.
- doi: 10.3349/ymj.2018.59.1.51
PURPOSE: 14-3-3ζ regulates cell signaling, cell cycle progression, and apoptosis, and its overexpression is associated with disease recurrence and poor clinical outcomes in some solid tumors. However, its clinicopathological role... -
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- zVAD-fmk, unlike BocD-fmk, does not inhibit caspase-6 acting on 14-3-3/Bad pathway in apoptosis of p815 mastocytoma cells
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Yee SB, Baek SJ, Park HT, Jeong SH, Jeong JH, Kim TH, Kim JM, Jeong BK, Park BS, Kwon TK, Yoon I, Yoo YH
- KMID: 1115941
- Exp Mol Med.
- 2006 Dec;38(6):634-642.
In a preliminary study, we found that benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone (zVAD- fmk), unlike Boc-aspartyl(OMe)-fluoromethylketone (BocD-fmk), at usual dosage could not prevent genistein-induced apoptosis of p815 mastocytoma cells. This study was undertaken to... -
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