- Anti-hyperlipidemic effect of soybean extract fermented by Bacillus subtilis MORI in db/db mice
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Nam Y, Jung H, Karuppasamy S, Lee JY, Kang KD, Hwang KY, Seong SI, Suh JG
- KMID: 1436709
- Lab Anim Res.
- 2012 Jun;28(2):123-129.
- doi: 10.5625/lar.2012.28.2.123
The purpose of this study was to investigate the anti-hyperlipidemic effect of soy bean extract solution fermented by Bacillus subtilis MORI (BTD-1E) in obese db/db mice. Eight-week-old male db/db mice... -
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- Red ginseng extract increases the functional components of silkworm Bombyx mori L. used as an anti-diabetes medicinal resource
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Son MW, Moon DI, Shin EH, Oh HG, Hong S, Han SJ, Lee HA, Chung YH, Kim O
- KMID: 2055095
- J Biomed Res.
- 2013 Mar;14(1):40-46.
The anti-diabetes mechanism of silkworm Bombyx mori L. powder and extracts was found to inhibit the activity of alpha-glycosidase. The major functional component of silkworm powder was 1-deoxynojirimycin (1-DNJ), which... -
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- Evaluation of General Toxicity and Genotoxicity of the Silkworm Extract Powder
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Heo HS, Choi JH, Oh JJ, Lee WJ, Kim SS, Lee DH, Lee HK, Song SW, Kim KH, Choi YK, Ryu KS, Kang BH
- KMID: 2317845
- Toxicol Res.
- 2013 Dec;29(4):263-278.
The silkworm extract powder contain 1-deoxynojirimycin (DNJ), a potent alpha-glycosidase inhibitor, has therapeutic potency against diabetes mellitus. Therefore, natural products containing DNJ from mulberry leaves and silkworm are consumed as... -
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- Lactosylceramide Mediates the Expression of Adhesion Molecules in TNF-alpha and IFNgamma-stimulated Primary Cultured Astrocytes
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Lee JK, Kim JK, Park SH, Sim YB, Jung JS, Suh HW
- KMID: 2071726
- Korean J Physiol Pharmacol.
- 2011 Oct;15(5):251-258.
- doi: 10.4196/kjpp.2011.15.5.251
Here we have investigated how lactosylceramide (LacCer) modulates gene expression of adhesion molecules in TNF-alpha and IFNgamma (CM)-stimulated astrocytes. We have observed that stimulation of astrocytes with CM increased the... -
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- Effects of a chemical chaperone on genetic mutations in alpha-galactosidase A in Korean patients with Fabry disease
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Park JY, Kim GH, Kim SS, Ko JM, Lee JJ, Yoo HW
- KMID: 756280
- Exp Mol Med.
- 2009 Jan;41(1):1-7.
- doi: 10.3858/emm.2009.41.1.001
Fabry disease is an X-linked inborn error of glycosphingolipid catabolism that results from mutations in the gene encoding the alpha-galactosidase A (GLA) enzyme. We have identified 15 distinct mutations in... -
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