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Enhanced Expressions and Histological Characteristics of Intravenously Administered Plasmid DNA in Rat Lung

Rha SJ, Wang YP

Cationic liposome-mediated gene transfection is a promising method for gene therapy. In this study, the transfection efficiency and histological patterns were evaluated in rat lung after intravenous administration via femoral...
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Downregulation of Orai1 expression in the airway alleviates murine allergic rhinitis

Wang Y, Lin L, Zheng C

Orai1 is the key subunit of the Ca2+-release-activated Ca2+ channel. Our previous report has demonstrated that Orai1 expression in the airway was upregulated in the ovalbumin (OVA)-induced allergic rhinitis (AR)...
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Galpha12 Protects Vascular Endothelial Cells from Serum Withdrawal-Induced Apoptosis through Regulation of miR-155

Lee HJ, Lee EJ, Seo M

PURPOSE: Apoptosis of vascular endothelial cells is a type of endothelial damage that is associated with the pathogenesis of cardiovascular diseases such as atherosclerosis. Heterotrimeric GTP-binding proteins (G proteins), including...
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