- Proangiogenic cells enhanced persistent and physiologic neovascularization compared with macrophages
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Choi YE, Cha YR, Lee KM, Kim HJ, Yoon CH
- KMID: 2155440
- Exp Mol Med.
- 2015 Sep;47(9):e186.
- doi: 10.1038/emm.2015.60
Proangiogenic cells (PACs) display surface markers and secrete angiogenic factors similar to those used by myelomonocytic cells, but, unlike myelomonocytic cells, PACs enhance neovascularization activity in experimental ischemic diseases. This... -
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- A novel way of therapeutic angiogenesis using an adeno-associated virus-mediated angiogenin gene transfer
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Cho YH, Park H, Cho ES, Kim WJ, Kang BS, Park BY, Kim YJ, Lee YI, Chang SI, Park K
- KMID: 1047093
- Exp Mol Med.
- 2007 Jun;39(3):412-418.
To develop a novel therapeutic angiogenesis for the treatment of cardiovascular diseases, angiogenin (ANG1) was examined as a potential therapeutic gene. An adeno-associated virus (AAV)-mediated gene delivery system was used... -
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- Vascular endothelial growth factor-induced angiogenic gene therapy in patients with peripheral artery disease
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Kim HJ, Jang SY, Park JI, Byun J, Kim DI, Do YS, Kim JM, Kim S, Kim BM, Kim WB, Kim DK
- KMID: 1094077
- Exp Mol Med.
- 2004 Aug;36(4):336-344.
This phase 1 clinical trial tested the safety of intramuscular gene transfer by using naked plasmid DNA encoding the gene for VEGF, and analyzed the potential therapeutic benefits in patients... -
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