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The Role of Microsatellite Instability in Early Gastric Cancer

Kim JJ

  • KMID: 1112582
  • Korean J Gastroenterol.
  • 2008 Mar;51(3):209-211.
No abstract availble.
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Clinical Implications of Microsatellite Instability in T1 Colorectal Cancer

Kang J, Lee HW, Kim IK, Kim NK, Sohn SK, Lee KY

PURPOSE: The estimation of regional lymph node metastasis (LNM) risk in T1 colorectal cancer is based on histologic examination and imaging of the primary tumor. High-frequency microsatellite instability (MSI-H) is...
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Microsatellite Instability of Gastric and Colorectal Cancers as a Predictor of Synchronous Gastric or Colorectal Neoplasms

Kim YB, Lee SY, Kim JH, Sung IK, Park HS, Shim CS, Han HS

BACKGROUND/AIMS: Microsatellite instability (MSI) plays a crucial role in gastrointestinal carcinogenesis. The aim of this study was to clarify whether MSI is a useful marker for predicting synchronous gastric and...
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Clinicopathological Characteristics of Colorectal Cancer with Family History: an Evaluation of Family History as a Predictive Factor for Microsatellite Instability

Park IJ, Kim HC, Yoon YS, Yu CS, Jang SJ, Kim JC

To determine whether family history of cancer may be a risk factor for the mutator phenotype in colorectal cancer, we recruited 143 consecutive colorectal cancer patients with a family history...
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Usefulness of Immunohistochemistry for Microsatellite Instability Screening in Gastric Cancer

Bae YS, Kim H, Noh SH, Kim H

BACKGROUND/AIMS: The usefulness of immunohistochemistry to screen for the microsatellite instability (MSI) phenotype in gastric cancer remains unclear. Moreover, the prognostic value of MSI phenotypes in gastric cancer has been...
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Significance of Microsatellite Instability in Early Gastric Cancer Treated by Endoscopic Submucosal Dissection

Kim KM, Kim YS, Cho JY, Jung IS, Kim WJ, Choi IS, Ryu CB, Kim JO, Lee JS, Jin SY, Shim CS, Kim BS

  • KMID: 1112575
  • Korean J Gastroenterol.
  • 2008 Mar;51(3):167-173.
BACKGROUND/AIMS: Microsatellite instability (MSI) is defined as a change of any length due to either insertion or deletion of repeating units, in a microsatellite within a tumor when compared to...
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Clinical Significance of Microsatellite Instability in Sporadic Epithelial Ovarian Tumors

Yoon BS, Kim YT, Kim JH, Kim SW, Nam EJ, Cho NH, Kim JW, Kim S

PURPOSE: We evaluated the expression of microsatellite instability (MSI) in sporadic ovarian tumors using 5 standard and 9 new MSI markers to determine the clinical significance of MSI in sporadic...
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Microsatellite Instability Status of Interval Colorectal Cancers in a Korean Population

Lee KW, Park SK, Yang HJ, Jung YS, Choi KY, Kim KE, Jung KU, Kim HO, Kim H, Chun HK, Park DI

BACKGROUND/AIMS: A subset of patients may develop colorectal cancer after a colonoscopy that is negative for malignancy. These missed or de novo lesions are referred to as interval cancers. The...
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Clinicopathologic Impacts of Poorly Differentiated Cluster-Based Grading System in Colorectal Carcinoma

Kim JW, Shin MK, Kim BC

Differentiation-based histologic grading of colorectal carcinoma (CRC) is widely used, but its clinical impact is limited by insufficient prognostic value, interobserver disagreement, and the difficulty of its application to CRC...
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Methylation Pattern of DNA Repair Genes and Microsatellite Instability in Hepatocelluar Carcinoma

Park JH, Cho SB, Lee WS, Park CH, Joo YE, Kim HS, Choi SK, Rew JS, Lee JH, Kim SJ

  • KMID: 1113480
  • Korean J Gastroenterol.
  • 2006 Nov;48(5):327-336.
BACKGROUND/AIMS: Epigenetic silencing of DNA repair genes, O6-methylguanine-DNA methyltransferase (MGMT), hMLH1 and hMSH3, by promoter hypermethylation have been observed in various cancers. However, the relationship between hypermethylation of DNA...
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