- Hypermethylation of p16(INK4a) in Korean Non-small Cell Lung Cancer Patients
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Hong YS, Roh MS, Kim NY, Lee HJ, Kim HK, Lee KE, Kwak JY, Kim JY
- KMID: 1785786
- J Korean Med Sci.
- 2007 Sep;22(Suppl):S32-S37.
- doi: 10.3346/jkms.2007.22.S.S32
Promoter hypermethylation of the p16(INK4a) gene was investigated in 81 sets of samples of tumor tissue and adjacent normal tissue from Korean patients with primary lung cancer, using the modified... -
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- Immunohistochemical Study of p53 Mutation and p16, p14 Alterations Encoded by INK4a-ARF in Mucin-ypersecreting Bile Duct Tumor
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Kim HJ, Kim MH, Song MH, Song DE, Yu E
- KMID: 1767495
- Korean J Gastroenterol.
- 2005 Mar;45(3):189-194.
BACKGROUND/AIMS: Mucin-hypersecreting bile duct tumor is rare, and has an unusual histologic characteristic of having various degrees of cellular atypia ranging from dysplasia to invasive carcinoma in the same specimen.... -
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- Detection of Aberrant p16INK4A Methylation in Sera of Patients with Liver Cirrhosis and Hepatocellular Carcinoma
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Chu HJ, Heo J, Seo SB, Kim GH, Kang DH, Song GA, Cho M, Yang US
- KMID: 1785699
- J Korean Med Sci.
- 2004 Feb;19(1):83-86.
- doi: 10.3346/jkms.2004.19.1.83
Hepatocellular carcinomas (HCCs) show genomic alterations, including DNA rearrangements associated with HBV DNA integration, loss of heterozygosity, and chromosomal amplification. The genes most frequently involved are those encoding tumor suppressors.... -
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