- Gene Therapy and Cell Transplantation for Alzheimer's Disease and Spinal Cord Injury
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Blesch A, Tuszynski
- KMID: 1726142
- Yonsei Med J.
- 2004 Jun;45(Suppl):S28-S31.
- doi: 10.3349/ymj.2004.45.Suppl.28
The targeted delivery of genes and the transplantation of suitable cell types into the adult nervous system have received considerable interest over the last years. The development of improved vector... -
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- Gene therapy of scarring: a lesson learned from fetal scarless wound healing
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Liu W, Cao Y, Longaker M
- KMID: 720678
- Yonsei Med J.
- 2001 Dec;42(6):634-645.
- doi: 10.3349/ymj.2001.42.6.634
Cutaneous wounding in adult humans and higher vertebrate animals results in scar formation. In contrast, both human and animal fetuses, at early gestational ages, exhibit skin wound healing without scarring.... -
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- Adenoviral mediated hepatocyte growth factor gene attenuates hyperglycemia and beta cell destruction in overt diabetic mice
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Park MK, Kim DK, Lee HJ
- KMID: 1119330
- Exp Mol Med.
- 2003 Dec;35(6):494-500.
Hepatocyte growth factor (HGF) is a potent mitogen and promoter of proliferation of insulin producing beta cells of pancreatic islets. To study the role of HGF, an adenoviral vector carrying... -
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- Enhanced Expressions and Histological Characteristics of Intravenously Administered Plasmid DNA in Rat Lung
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Rha SJ, Wang YP
- KMID: 2157563
- J Korean Med Sci.
- 2001 Oct;16(5):567-572.
- doi: 10.3346/jkms.2001.16.5.567
Cationic liposome-mediated gene transfection is a promising method for gene therapy. In this study, the transfection efficiency and histological patterns were evaluated in rat lung after intravenous administration via femoral... -
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- Biologic Therapy for Brain Cancers - Based on Cellular and Immunobiology
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Okada H
- KMID: 1726149
- Yonsei Med J.
- 2004 Jun;45(Suppl):S68-S70.
- doi: 10.3349/ymj.2004.45.Suppl.68
The overall goal of our research projects is to develop effective immunotherapeutic regimens, particularly combining vaccine and gene therapy/ cell therapy strategies. For the development of clinically effective immunotherapy for... -
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- Gene Therapy for Head and Neck Squamous Cell Carcinoma Using KITENIN (KAI1 COOH-Terminal Interacting Tetraspanin)-Antisense Therapy
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Lee JK, Lee DH, Sun EG, Bae JA, Lim SC, Min JJ, Sung MW, Kim KK
- KMID: 1777018
- Yonsei Med J.
- 2011 May;52(3):463-468.
- doi: 10.3349/ymj.2011.52.3.463
PURPOSE: KAI1 COOH-terminal interacting tetraspanin (KITENIN) has been found to act as a promoter of metastasis in murine models of colon cancer and squamous cell carcinoma (SCC). The suppression of... -
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- Vascular endothelial growth factor-induced angiogenic gene therapy in patients with peripheral artery disease
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Kim HJ, Jang SY, Park JI, Byun J, Kim DI, Do YS, Kim JM, Kim S, Kim BM, Kim WB, Kim DK
- KMID: 1094077
- Exp Mol Med.
- 2004 Aug;36(4):336-344.
This phase 1 clinical trial tested the safety of intramuscular gene transfer by using naked plasmid DNA encoding the gene for VEGF, and analyzed the potential therapeutic benefits in patients... -
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- Preclinical studies for pharmacokinetics and biodistribution of Ad-stTRAIL, an adenovirus delivering secretable trimeric TRAIL for gene therapy
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Kim CY, Park SH, Jeong M, Kwon OS, Doh H, Kang SH, Robbins PD, Kim BM, Seol DW, Kim BG
- KMID: 1123370
- Exp Mol Med.
- 2011 Oct;43(10):580-586.
- doi: 10.3858/emm.2011.43.10.065
Malignant glioma is the most frequent type in brain tumors. The prognosis of this tumor has not been significantly improved for the past decades and the average survival of patients... -
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- Efficient gene delivery in differentiated human embryonic stem cells
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Kim JH, Do HJ, Choi SJ, Cho HJ, Park KH, Yang HM, Lee SH, Kim DK, Kwack K, Oh SK, Moon SY, Cha KY, Chung HM
- KMID: 1033099
- Exp Mol Med.
- 2005 Feb;37(1):36-44.
Human embryonic stem (hES) cells are capable of differentiating into pluralistic cell types, however, spontaneous differentiation generally gives rise to a limited number of specific differentiated cell types and a... -
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