- Regulation of ATP-citrate lyase gene transcription
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Kim KS, Kang JG, Moon YA, Park SW, Kim YS
- KMID: 699895
- Yonsei Med J.
- 1996 Jun;37(3):214-224.
- doi: 10.3349/ymj.1996.37.3.214
It has been suggested that glucose metabolites and insulin are the most important factors inducing ATP-citrate lyase (ACL) by a high carbohydrate diet. We have used a primary culture of... -
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- Regulation of fatty acid synthase at transcriptional and post-transcriptional levels in rat liver
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Kim KS, Park SW, Kim YS
- KMID: 1120230
- Yonsei Med J.
- 1992 Sep;33(3):199-208.
- doi: 10.3349/ymj.1992.33.3.199
The regulation of fatty acid synthase in rat liver was investigated at transcriptional and post-transcriptional levels. When rats were fasted for 3 days and refed on a high-carbohydrate diet, the... -
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- Regulation of expression of matrix metalloproteinase-9 by JNK in Raw 264.7 cells: presence of inhibitory factor(s) suppressing MMP-9 induction in serum and conditioned media
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Lee YS, Lan Tran H, Van Ta Q
- KMID: 1088601
- Exp Mol Med.
- 2009 Apr;41(4):259-268.
- doi: 10.3858/emm.2009.41.4.029
Matrix metalloproteinase-9 (MMP-9) secreted from macrophages plays an important role in tissue destruction and inflammation through degradation of matrix proteins and proteolytic activation of cytokines/chemokines. Whereas the MEK-ERK and PI3K-Akt... -
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- Enhanced tyrosine hydroxylase expression in PC12 cells co-cultured with feline mesenchymal stem cells
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Jin GZ, Yin XJ, Yu XF, Cho SJ, Lee HS, Lee HJ, Kong IK
- KMID: 1106218
- J Vet Sci.
- 2007 Dec;8(4):377-382.
- doi: 10.4142/jvs.2007.8.4.377
Mesenchymal stem cells (MSCs) secrete a variety of neuroregulatory molecules, such as nerve growth factor, brain-derived neurotrophic factor, and glial cell-derived neurotrophic factor, which upregulate tyrosine hydroxylase (TH) gene expression... -
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- The Ketogenic Diet Suppresses the Cathepsin E Expression Induced by Kainic Acid in the Rat Brain
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Jeong HJ, Kim H, Kim YK, Park SK, Kang DW, Yoon D
- KMID: 1071415
- Yonsei Med J.
- 2010 Sep;51(5):653-660.
- doi: 10.3349/ymj.2010.51.5.653
PURPOSE: The ketogenic diet has long been used to treat epilepsy, but its mechanism is not yet clearly understood. To explore the potential mechanism, we analyzed the changes in gene... -
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- Expression and Regulation of Endothelial Nitric Oxide Synthase by Vascular Endothelial Growth Factor in ECV 304 Cells
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Park JS, Hong GR, Baek SW, Shin DG, Kim YJ, Shim BS
- KMID: 648670
- J Korean Med Sci.
- 2002 Apr;17(2):161-167.
- doi: 10.3346/jkms.2002.17.2.161
Nitric oxide (NO) seems to play a pivotal role in the vascular endothelial growth factor (VEGF)-induced endothelial cell proliferation. This study was designed to investigate the role and intracellular signal... -
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- Expression of hOGG1 protein during differentiation of HL-60 cells
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Lee YS, Lee KH, Chung MH
- KMID: 1097257
- Exp Mol Med.
- 2003 Apr;35(2):98-105.
Human 8-oxo-G-DNA glycosylase 1 (hOGG1) is a DNA glycosylase to cleave 8-oxo-7,8-dihydroguanine (8-oxo-G), a mutagenic DNA adduct formed by oxidant stresses. Here, we examined hOGG1 protein expression and repair activity... -
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- Impacts of Cytosolic Phospholipase A2, 15-Prostaglandin Dehydrogenase, and Cyclooxygenase-2 Expressions on Tumor Progression in Colorectal Cancer
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Lim SC, Cho H, Lee TB, Choi CH, Min YD, Kim SS, Kim KJ
- KMID: 1071420
- Yonsei Med J.
- 2010 Sep;51(5):692-699.
- doi: 10.3349/ymj.2010.51.5.692
PURPOSE: In addition to cyclooxygenase-2 (COX-2) which is related to prostaglandin E2 synthesis, other enzymes such as cytosolic phospholipase A2 (cPLA2), microsomal prostaglandin E2 synthase-1 (mPGES-1), and 15-prostaglandin dehydrogenase (15-PGDH)... -
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- Aldosterone-induced TGF-beta1 Expression is Regulated by Mitogen-Activated Protein Kinases and Activator Protein-1 in Mesangial Cells
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Han JS, Cho BS, Yang CW, Kim YS
- KMID: 1778162
- J Korean Med Sci.
- 2009 Jan;24(Suppl 1):S195-S203.
- doi: 10.3346/jkms.2009.24.S1.S195
Aldosterone has been shown to stimulate renal TGF-beta1 expression. However, the mechanisms for aldosterone-induced TGF-beta1 expression have not been clearly determined in mesangial cells. We examined the role of extracellular-signal... -
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- 15-Deoxy-delta 12,14-ProstaglandinJ2 Regulates Dedifferentiation through Peroxisome Proliferator-Activated Receptor-gamma-Dependent Pathway but Not COX-2 Expression in Articular Chondrocytes
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Lee JH, Yu SM, Yoon EK, Lee WK, Jung JC, Kim SJ
- KMID: 1713299
- J Korean Med Sci.
- 2007 Oct;22(5):891-897.
- doi: 10.3346/jkms.2007.22.5.891
Peroxisome proliferator-activated receptors-gamma (PPAR-gamma) is critical for phenotype determination at early differentiation stages of mesenchymal cells, whereas its physiological role is unclear. Therefore, we investigated the role of 15-deoxy-delta 12,14-prostaglandinJ2... -
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