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Transcriptional regulation of Zic3 by heterodimeric AP-1(c-Jun/c-Fos) during Xenopus development

Lee SY, Lee HS, Moon JS, Kim JI, Park JB, Lee JY, Park MJ, Kim J

  • KMID: 1123768
  • Exp Mol Med.
  • 2004 Oct;36(5):468-475.
The heterodimeric c-Jun/c-Fos, an activator protein-1 (AP-1) has been implicated in mesoderm induction (Dong et al., 1996; Kim et al., 1998) whereas the homodimer of c-Jun was reported to be...
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Polycystin-1 Expression in Fetal, Adult and Autosomal Dominant Polycystic Kidney

Chae SW, Cho EY, Park MS, Lee KB, Kim H, Kim U

The mutation of the PKD1 gene causes autosomal dominant polycystic kidney disease (ADPKD), and the PKD1 gene encodes polycystin-1 (PC-1). PC-1 is thought to be a cell-cell/matrix adhesion receptor molecule...
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A simplified one-step nuclear transfer procedure alters the gene expression patterns and developmental potential of cloned porcine embryos

Park SK, Roh S, Park JI

Various somatic cell nuclear transfer (SCNT) techniques for mammalian species have been developed to adjust species-specific procedures to oocyte-associated differences among species. Species-specific SCNT protocols may result in different expression...
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Nuclear receptor regulation of stemness and stem cell differentiation

Jeong Y, Mangelsdorf DJ

Stem cells include a diverse number of toti-, pluri-, and multi-potent cells that play important roles in cellular genesis and differentiation, tissue development, and organogenesis. Genetic regulation involving various transcription...
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Expression of KA1 kainate receptor subunit in the substantia gelatinosa of the trigeminal subnucleus caudalis in mice

Park SA, Park SJ, Han SK

The KA1 kainate receptor (KAR) subunit in the substantia gelatinosa (SG) of the trigeminal subnucleus caudalis (Vc) has been implicated in the processing of nociceptive information from the orofacial region....
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Genomic organization and expression of parkin in Drosophila melanogaster

Bae YJ, Park KS, Kang SJ

  • KMID: 1093612
  • Exp Mol Med.
  • 2003 Oct;35(5):393-402.
We report here the isolation, characterization on genomic structure and expression of the D. melanogaster homolog of human parkin. The 2,122 bp parkin gene sequence contains six exons that form...
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Spatio-temporal expression patterns of Runx2 isoforms in early skeletogenesis

Choi KY, Lee SW, Park MH, Bae YC, Shin HI, Nam SH, Kim YJ, Kim HJ, Ryoo HM

  • KMID: 1121096
  • Exp Mol Med.
  • 2002 Dec;34(6):426-433.
Skeletogenesis occurs through either intramembranous or endochondral ossification. In addition, some parts of the skeletal components maintain their cartilaginous characteristics throughout life without mineralization. Runx2 is known to be...
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Identification of abnormal gene expression in bovine transgenic somatic cell nuclear transfer embryos

Cho J, Kang S, Lee BC

This study was conducted to investigate the expression of three genes related to early embryonic development in bovine transgenic cloned embryos. To accomplish this, development of bovine transgenic somatic cell...
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Shank 2 expression coincides with neuronal differentiation in the developing retina

Kim JH, Kim JH, Yang E, Park JH, Yu YS, Kim KW

The retinal activity for vision requires a precise synaptic connectivity. Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron. However, the correlation...
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Ubiquitylation of Fe65 adaptor protein by neuronal precursor cell expressed developmentally down regulated 4-2 (Nedd4-2) via the WW domain interaction with Fe65

Lee EJ, Hyun S, Chun J, Shin SH, Kang SS

Fe65 has been characterized as an adaptor protein, originally identified as an expressed sequence tag (EST) corresponding to an mRNA expressed at high levels in the rat brain. It contains...
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Differential patterns of nestin and glial fibrillary acidic protein expression in mouse hippocampus during postnatal development

Kim JS, Kim J, Kim Y, Yang M, Jang H, Kang S, Kim JC, Kim SH, Shin T, Moon C

Intermediate filaments, including nestin and glial fibrillary acidic protein (GFAP), are important for the brain to accommodate neural activities and changes during development. The present study examined the temporal changes...
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AKAP12 regulates vascular integrity in zebrafish

Kwon HB, Choi YK, Lim JJ, Kwon SH, Her S, Kim HJ, Lim KJ, Ahn JC, Kim YM, Bae MK, Park JA, Jeong CH, Mochizuki , Kim KW

The integrity of blood vessels controls vascular permeability and extravasation of blood cells, across the endothelium. Thus, the impairment of endothelial integrity leads to hemorrhage, edema, and inflammatory infiltration. However,...
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