- Transformation into large-cell neuroendocrine carcinoma associated with acquired resistance to erlotinib in nonsmall cell lung cancer
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Lim JU, Woo IS, Jung YH, Byeon JH, Park CK, Kim TJ, Kim HR
- KMID: 2070144
- Korean J Intern Med.
- 2014 Nov;29(6):830-833.
- doi: 10.3904/kjim.2014.29.6.830
No abstract available. -
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- Combination treatment with 2-methoxyestradiol overcomes bortezomib resistance of multiple myeloma cells
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Song IS, Jeong YJ, Jeong SH, Heo HJ, Kim HK, Lee SR, Ko TH, Youm JB, Kim N, Ko KS, Rhee BD, Han J
- KMID: 2154269
- Exp Mol Med.
- 2013 Oct;45(10):e50.
Bortezomib is a proteasome inhibitor used for the treatment of relapsed/refractory multiple myeloma (MM). However, intrinsic and acquired resistance to bortezomib has already been observed in MM patients. In a... -
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- Treatment Outcome of Multidrug Resistance Related mRNA Expression and c-Jun-N-Terminal Kinase Activity in Patients with Acute Myeloid Leukemia
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Do JH, Oh SH, Song EJ, Chung JS, Kang CD, Lee EY
- KMID: 1781489
- Korean J Lab Med.
- 2007 Aug;27(4):229-236.
- doi: 10.3343/kjlm.2007.27.4.229
BACKGROUND: The multidrug resistance (mdr1), multidrug resistance associated protein (mrp1), and glutathione-s-transferase (gst) pi genes have been associated with treatment failure in acute myeloid leukemia (AML). c-jun N-terminal kinase... -
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- Blockade of VEGFR-1 and VEGFR-2 Enhances Paclitaxel Sensitivity in Gastric Cancer Cells
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Hwang JE, Lee JH, Park MR, Kim DE, Bae WK, Shim HJ, Cho SH, Chung IJ
- KMID: 1503899
- Yonsei Med J.
- 2013 Mar;54(2):374-380.
- doi: 10.3349/ymj.2013.54.2.374
PURPOSE: Hypoxia-inducible factor-1alpha (HIF-1alpha) increases transcription of the vascular endothelial growth factor (VEGF) gene. Inhibition of VEGF abolishes VEGF mediated induction of HIF-1alpha. Recent reports suggested that HIF-1alpha also mediated... -
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