Korean J Med Mycol.  2000 Sep;5(3):144-149.

Chromoblastomycosis Treated with Occlusive Dressing of Amphotericin B Cream

• Kim SW
• Oh SH
• Choi SK
• Lee YH
• Yoon JH
• Bang YJ
• Suh SB

Abstract

We report a case of chromoblastomycosis in a 65 year-old woman. She had a 3x4 cm sized, annular, erythematous, plaque with crusts and ulcers on the right lower arm. The lesion had grown slowly for 2 years. In fungal and histopathologic examinations, several muriform cells were found in dermis as well as in scales and crusts on the lesional skin surface. Isolated fungus was identified as Fonsecaea pedrosoi. We treated the patient occlusive dressing of amphotericin B (3%) ointment for 8 weeks and achieved a good response without any evidence of recurrence. We propose that the occlusive dressing therapy of amphotericin B cream is a good modality among the various treatments of small localized chromoblastomycosis.

Keyword

Chromoblastomycosis; Fonsecaea pedrosoi; Occlusive dressing; Amphotercin B

MeSH Terms

Aged
Amphotericin B*
Arm
Chromoblastomycosis*
Dermis
Female
Fungi
Humans
Occlusive Dressings*
Recurrence
Skin
Ulcer
Weights and Measures
Amphotericin B