Korean J Dermatol.  2003 Sep;41(9):1228-1231.

Neonatal Lupus Erythematosus: Showing Target-like Skin Lesions

Affiliations
  • 1Department of Dermatology, College of Medicine Chungbuk National University, Cheongju, Korea.
  • 2Department of Pediatrics, College of Medicine Chungbuk National University, Cheongju, Korea.
  • 3Department of Internal Medicine, College of Medicine Chungbuk National University, Cheongju, Korea.
  • 4Medical Research Institute, College of Medicine Chungbuk National University, Cheongju, Korea.

Abstract

Neonatal lupus erythematosus(NLE) is a rare disease characterized by the transplacental passage from the mother to the fetus of autoantibodies, particularly autoantibodies of Ro family. The patient with NLE exhibits one or more of the following findings: congenital heart block, cutaneous lupus lesions, hepatobiliary disease and hematologic disorders(thrombocytopenia, anemia). We report a case of NLE in a 2-week-old male infant, born of a clinically asymptomatic mother, presenting multiple, round, target-like lesions which have not been reported in the English and Korean literature. Both infant and mother were positive for anti-SSA/Ro and anti-SSB/La.

Keyword

Neonatal lupus erythematosus; Target-like lesions; Anti-SSA/Ro antibody

MeSH Terms

Autoantibodies
Fetus
Heart Block
Humans
Infant
Male
Mothers
Rare Diseases
Skin*
Autoantibodies
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