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Treatment of immune-mediated keratitis (IMMK) in dogs with immunosuppressants observed with spectral domain optical coherence tomography (SD-OCT)

Kim H, Jeong Y, Lee E, Seo K, Kang S

Two dogs presented with bilateral pattern-forming corneal opacity. Treatment with topical immunosuppressants was initiated after a complete ophthalmic examination. The response to treatment was assessed by analyzing serial images using...
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Metastatic intestinal adenocarcinoma with osseous metaplasia in two Domestic Korean Shorthair cats

Jung JH, Kim NY, Yang Y, Seo D, Choi G, Hong H, Moon T, Kim HM, Han J, Hong J, Kim Y

Two Domestic Korean Shorthair cats presented with dyschezia and vomiting. Computed tomography revealed a colonic mass with calcification and lymph node metastasis in case 1, and a small intestinal mass...
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Hematological differentiation of bladder rupture and complete/partial urethral obstruction in castrated Hanwoo (Korean indigenous cattle) with urolithiasis

Kim YJ, Ha SM, Ku JY, Yoon JS, Park J

This case report describes the hematological and radiological examination of urinary bladder rupture and complete urethral obstruction. associated with urolithiasis in Hanwoo. Hyponatremia, hypochloremia, azotemia, and hyperglycemia were observed in both...
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Use of cutting-edge RNA-sequencing technology to identify biomarkers and potential therapeutic targets in canine and feline cancers and other diseases

Choi Y, Nam MW, Lee HK, Choi KC

With the growing interest in companion animals and the rapidly expanding animal healthcare and pharmaceuticals market worldwide. With the advancements in RNAsequencing (RNA-seq) technology, it has become a valuable tool...
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Fibrinous pleuritis associated with Streptococcus canis in a leopard cat (Prionailurus bengalensis euptilurus)

Seo MG, Han KY, Kim SH, Kang CK, Kim JH, Hong IH

Leopard cat (Prionailurus bengalensis euptilurus) is a small wild cat assessed as an endangered wildlife in Korea. There have been very few reports of their diseases. Herein, we describe fibrinous...
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Inhibition of caspase-1-dependent apoptosis suppresses peste des petits ruminants virus replication

Li L, Li S, Han S, Li P, Du G, Wu J, Cao X, Shang Y

Background: Peste des petits ruminants (PPR), caused by the PPR virus (PPRV), is an acute and fatal contagious disease that mainly infects goats, sheep, and other artiodactyls. Peripheral blood mononuclear cells...
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Review of outcomes of using lower ethanol concentration (83%) in percutaneous ultrasound-guided renal cyst sclerotherapy in dogs

Yoon S, Kwak J, Im D, Yoon H

Background: Percutaneous renal cyst sclerotherapy (PRCS) as a treatment for renal cysts is usually performed with a high concentration of ethanol (≥ 90%). This study reviewed cases in which a...
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Nutritional evaluation of new alternative types of dog foods including raw and cooked homemadestyle diets

Choi B, Kim S, Jang G

Background: New alternative types of pet foods such as raw and cooked homemadestyle diets containing human food ingredients have been introduced due to a trend of pet humanization and diversification...
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Comparison of blood parameters according to fecal detection of Mycobacterium avium subspecies paratuberculosis in subclinically infected Holstein cattle

Ha S, Kang S, Jung M, Kim SB, Lee HG, Park HT, Lee JH, Choi KC, Park J, Kim UH, Yoo HS

Background: Mycobacterium avium subspecies paratuberculosis (MAP) causes a chronic and progressive granulomatous enteritis and economic losses in dairy cattle in subclinical stages. Subclinical infection in cattle can be detected using serum...
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Subcutaneous Streptococcus dysgalactiae GAPDH vaccine in mice induces a proficient innate immune response

An R, Guo Y, Gao M, Wang J

Background: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) on the surface of Streptococcus dysgalactiae, coded with gapC, is a glycolytic enzyme that was reported to be a moonlighting protein and virulence factor. Objective: This study...
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Biochemical and structural comparisons of non-nucleoside reverse transcriptase inhibitors against feline and human immunodeficiency viruses

Rattanabunyong S, Choengpanya K, Suwattanasophon C, Kiriwan D, Wolschann P, Lamtha T, Shaikh AR, Rattanasrisomporn J, Choowongkomon K

Background: Feline immunodeficiency virus (FIV) causes an acquired immunodeficiencylike syndrome in cats. FIV is latent. No effective treatment has been developed for treatment the infected cats. The first and second...
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Comparison of bone subtraction CT angiography with standard CT angiography for evaluating circle of Willis in normal dogs

An S, Hwang G, Kim R, Hwang TS, Lee HC

Background: Bone subtraction computed tomography angiography (BSCTA) is a useful alternative technique for improving visualization of vessels surrounded by skull bone. However, no studies have compared computed tomography angiography (CTA) and...
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Placental development in the early stages of red-rumped agouti pregnancy (Dasyprocta leporina Linnaeus, 1758)

Oliveira GBd, Araújo Júnior HNd, Moura CEBd, Favaron PO, Pereira AF, Oliveira MFd

Background: Hystricomorpha rodents display a similar placentation model to humans. The present study was carried out considering the scarcity of information concerning the placental development in agouti. Objective: Describe the microscopy of...
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Analysis of miRNA expression in the trachea of Ri chicken infected with the highly pathogenic avian influenza H5N1 virus

Kang S, Vu TH, Heo J, Kim C, Lillehoj HS, Hong YH

Background: Highly pathogenic avian influenza virus (HPAIV) is considered a global threat to both human health and the poultry industry. MicroRNAs (miRNA) can modulate the immune system by affecting gene...
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Kalkitoxin attenuates calcification of vascular smooth muscle cells via RUNX-2 signaling pathways

Shrestha SK, Kim SW, Soh Y

Background: Kalkitoxin (KT) is an active lipopeptide isolated from the cyanobacterium Lyngbya majuscula found in the bed of the coral reef. Although KT suppresses cell division and inflammation, KT’s mechanism...
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Protection provided by a commercial modified-live porcine reproductive and respiratory syndrome virus (PRRSV) 1 vaccine (PRRSV1-MLV) against a Japanese PRRSV2 field strain

Miranda J, Romero S, Lucas Ld, Saito F, Fenech M, Díaz I

Background: Porcine reproductive and respiratory syndrome virus (PRRSV) vaccines do not provide full cross-protection, mainly due to the virus genetic variability. Despite this, vaccines based on modified-live PRRSV (PRRSV-MLV) reduce...
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