- Apoptotic Effect of Macrophages against Mycobacterium tuberculosis
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Kim LH, Shin SJ
- KMID: 2366879
- J Bacteriol Virol.
- 2016 Dec;46(4):312-318.
- doi: 10.4167/jbv.2016.46.4.312
Mycobacterium tuberculosis (Mtb) causing tuberculosis as an intracellular pathogen initially infects alveolar macrophages following aerosol inhalation. Thus, macrophages play a critical role in the establishment of Mtb infection and macrophage... -
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- Time Point Expression of Apoptosis Regulatory Proteins in a Photochemically-Induced Focal Cerebral Ischemic Rat Brain
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Kim HS, Park MS, Lee JK, Kim HJ, Park JT, Lee MC
- KMID: 2172222
- Chonnam Med J.
- 2011 Dec;47(3):144-149.
- doi: 10.4068/cmj.2011.47.3.144
Apoptosis after global or focal cerebral ischemia plays a crucial role in mediating cell death. In this study, we observed the time point expression of physiologic events involving apoptosis regulatory... -
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- Alterations of Cell Cycle Regulation and Apoptosis Related Factors in Skin Tumors
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Yang TH, Chang SH, Yoon TY
- KMID: 2303180
- Korean J Dermatol.
- 2001 Jan;39(1):28-38.
BACKGROUND: Tumor growth and progression is dependent on a variety of factors including; increased cell survival, i. e. resistance to undergo apoptosis, increased proliferation, and the inability to undergo growth... -
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- Curcumin Induces Apoptosis and Inhibits Metalloproteinase Activity in Renal Cancer Cell Line
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Kim DG, Kwon TK, Park JW, Lee KS
- KMID: 2292626
- Korean J Urol.
- 2002 May;43(5):423-430.
PURPOSE: Curcumin is the major constitute of turmeric powder extracted from the rhizomes of the plant Curcuma longa. We investigated that the effect of curcumin on regulatory protein of cell... -
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- Effect of BMI1 Knockdown on Cell Proliferation, Apoptosis, Invasiveness, and Migration of U251 Glioma Cells
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Kim DJ, Jun YH, Kim DH, Kim JJ
- KMID: 2283755
- Korean J Phys Anthropol.
- 2015 Jun;28(2):69-78.
- doi: 10.11637/kjpa.2015.28.2.69
BMI1 belongs to the polycomb-repressive complex 1 (PRC1) family of genes that are conserved chromatin silencers. These are essential for maintaining both the normal and cancerous stem cell state. In... -
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- Immunohistochemical Analysis of BAD Protein Expression in Gastric Carcinomas
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Yoo NJ, Lee JW, Park WS, Lee JY, Lee SH
- KMID: 2372719
- J Korean Gastric Cancer Assoc.
- 2003 Jun;3(2):75-79.
PURPOSE: Evidence exists that dysregulation of apoptosis is involved in the pathogenesis of cancer development. The Bcl-XL/Bcl-2-associated death promoter (BAD), a member of the Bcl-2 family, is a critical regulatory... -
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- Knockdown of 14-3-3zeta enhances radiosensitivity and radio-induced apoptosis in CD133+ liver cancer stem cells
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Lee YK, Hur W, Lee SW, Hong SW, Kim SW, Choi JE, Yoon SK
- KMID: 2155342
- Exp Mol Med.
- 2014 Feb;46(2):e77.
- doi: 10.1038/emm.2013.151
14-3-3zeta is related to many cancer survival cellular processes. In a previous study, we showed that silencing 14-3-3zeta decreases the resistance of hepatocellular carcinoma (HCC) to chemotherapy. In this study,... -
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- The expressions of HSP70 and alphaB-crystallin in myocarditis associated with foot-and-mouth disease virus in lambs
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Gulbahar M, Kabak YB, Karayigit , Yarim M, Guvenc T, Parlak U
- KMID: 1067339
- J Vet Sci.
- 2011 Mar;12(1):65-73.
- doi: 10.4142/jvs.2011.12.1.65
This study describes the expression of heat shock protein70 (HSP70) and alpha-basic-crystallin (alpha-BC) and their association with apoptosis and some related adaptor proteins in the pathogenesis of foot-and-mouth disease virus... -
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- Purpurogallin Protects Keratinocytes from Damage and Apoptosis Induced by Ultraviolet B Radiation and Particulate Matter 2.5
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Zhen AX, Piao MJ, Hyun YJ, Kang KA, Ryu YS, Cho SJ, Kang HK, Koh YS, Ahn MJ, Kim TH, Hyun JW
- KMID: 2455095
- Biomol Ther.
- 2019 Jul;27(4):395-403.
- doi: 10.4062/biomolther.2018.151
Purpurogallin, a natural phenol obtained from oak nutgalls, has been shown to possess antioxidant, anticancer, and anti-inflammatory effects. Recently, in addition to ultraviolet B (UVB) radiation that induces cell apoptosis... -
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- Effect of Hypoxia-induced XIAP Expression on Apoptosis of Trophoblast Cells in Placenta
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Lee JS, Jeon SY, Choi JH, Lee YJ, Cha DH, Kim GJ
- KMID: 2070999
- Korean J Reprod Med.
- 2010 Sep;37(3):217-229.
OBJECTIVE: Apoptosis plays an important role for the maintenance of the normal pregnancy. Expression of X-linked inhibitor of apoptosis (XIAP) is able to effectively prevent apoptosis and controls trophoblast cells... -
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- Red pepper seed water extract inhibits preadipocyte differentiation and induces mature adipocyte apoptosis in 3T3-L1 cells
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Kim HJ, You MK, Lee YH, Kim HJ, Adhikari D, Kim HA
- KMID: 2448694
- Nutr Res Pract.
- 2018 Dec;12(6):494-502.
- doi: 10.4162/nrp.2018.12.6.494
BACKGROUND/OBJECTIVES: Reducing the number of adipocytes by inducing apoptosis of mature adipocytes as well as suppressing differentiation of preadipocytes plays an important role in preventing obesity. This study examines the... -
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- Anti-Cancer Effect of 3-(4-dimethylamino phenyl)-N-hydroxy-2-propenamide in MCF-7 Human Breast Cancer
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Min KN, Joung KE, Kim DK, Sheen YY
- KMID: 2380177
- Environ Health Toxicol.
- 2012 ;27(1):e2012010.
OBJECTIVES: In recent years, a number of structurally diverse Histone deacetylase (HDAC) inhibitors have been identified and these HDAC inhibitors induce growth arrest, differentiation and/or apoptosis of cancer cells in... -
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- The Anti-apoptotic Effect of Ghrelin on Restraint Stress-Induced Thymus Atrophy in Mice
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Lee JH, Kim TJ, Kim JW, Yoon JS, Kim HS, Lee KM
- KMID: 2349885
- Immune Netw.
- 2016 Aug;16(4):242-248.
- doi: 10.4110/in.2016.16.4.242
Thymic atrophy is a complication that results from exposure to many environmental stressors, disease treatments, and microbial challenges. Such acute stress-associated thymic loss can have a dramatic impact on the... -
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- Autophagy Inhibition with Monensin Enhances Cell Cycle Arrest and Apoptosis Induced by mTOR or Epidermal Growth Factor Receptor Inhibitors in Lung Cancer Cells
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Choi HS, Jeong EH, Lee TG, Kim SY, Kim HR, Kim CH
- KMID: 2320432
- Tuberc Respir Dis.
- 2013 Jul;75(1):9-17.
BACKGROUND: In cancer cells, autophagy is generally induced as a pro-survival mechanism in response to treatment-associated genotoxic and metabolic stress. Thus, concurrent autophagy inhibition can be expected to have a... -
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- Human Brain Astrocytes Mediate TRAIL-mediated Apoptosis after Treatment with IFN-gamma
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Lee J, Shin JS, Choi IH
- KMID: 1715853
- Yonsei Med J.
- 2006 Jun;47(3):354-358.
- doi: 10.3349/ymj.2006.47.3.354
TNF-related apoptosis inducing ligand (TRAIL) expressions were studied in primary human brain astrocytes in response to pro-inflammatory cytokines. When astrocytes were treated with IL-1beta TNF-alphaor IFN-gamma TRAIL was induced in... -
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- 17-DMAG has the Potentiated Anticancer Effects Against Hepatocellular Carcinoma Cells by Transfection of the Gene Encoding Hepatitis B Viral X Protein
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Lee CS, Kim OH, Hong HE, Jeon SJ, Won SS, Kim SJ
- KMID: 2396567
- J Liver Cancer.
- 2017 Sep;17(2):126-135.
- doi: 10.17998/jlc.17.2.126
BACKGROUND/AIMS: Hepatitis B viral protein X (HBx) is implicated in the pathogenesis of hepatocellular carcinoma (HCC) as well as the elevation of heat shock proteins (HSPs) after hepatitis B virus... -
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- Radiation-induced Apoptosis is Differentially Modulated by PTK Inhibitors K562 Cells
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Lee HS, Moon CW, Hur WJ, Jeong SJ, Jeong MH, Lee JH, Lim YJ, Park HJ
- KMID: 1769007
- J Korean Soc Ther Radiol Oncol.
- 2000 Mar;18(1):51-58.
PURPOSE: The effect of PTK inhibitors (herbimycin A and genistein) on the induction of radiation-induce d apoptosis in Ph-positive K562 leukemia cell line was investigated. MATERIALS AND METHODS: K562 cells in exponential... -
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- Diphenyleneiodonium Inhibits Apoptotic Cell Death of Gastric Epithelial Cells Infected with Helicobacter pylori in a Korean Isolate
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Cho SO, Lim JW, Kim H
- KMID: 2366360
- Yonsei Med J.
- 2015 Jul;56(4):1150-1154.
- doi: 10.3349/ymj.2015.56.4.1150
NADPH oxidase produces a large amount of reactive oxygen species (ROS) in Helicobacter pylori (H. pylori)-induced gastric epithelial cells. Even though ROS mediate apoptotic cell death, direct involvement of NADPH... -
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- Cis-3-O-p-hydroxycinnamoyl Ursolic Acid Induced ROS-Dependent p53-Mediated Mitochondrial Apoptosis in Oral Cancer Cells
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Wang CY, Lin CS, Hua CH, Jou YJ, Liao CR, Chang YS, Wan L, Huang SH, Hour MJ, Lin CW
- KMID: 2432067
- Biomol Ther.
- 2019 Jan;27(1):54-62.
- doi: 10.4062/biomolther.2017.237
Cis-3-O-p-hydroxycinnamoyl ursolic acid (HCUA), a triterpenoid compound, was purified from Elaeagnus oldhamii Maxim. This traditional medicinal plant has been used for treating rheumatoid arthritis and lung disorders as well as... -
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- Transglutaminase 2 inhibits apoptosis induced by calciumoverload through down-regulation of Bax
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Cho SY, Lee JH, Bae HD, Jeong EM, Jang GY, Kim CW, Shin DM, Jeon JH, Kim IG
- KMID: 983956
- Exp Mol Med.
- 2010 Sep;42(9):639-650.
- doi: 10.3858/emm.2010.42.9.063
An abrupt increase of intracellular Ca2+ is observed in cells under hypoxic or oxidatively stressed conditions. The dysregulated increase of cytosolic Ca2+ triggers apoptotic cell death through mitochondrial swelling and... -
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