Making a model that is an accurate replica of the oral structure requires precision and efficiency. Nowadays, rapid technological advances bring digitalization in dentistry. One of the most important works in digital dentistry is three-dimensional modeling of the oral cavity and digitizing the 3D data. Among the three components of CAD/CAM, data capture component (digitizers), design component (CAD software), manufacturing component (CAM), the basic component that has a significant impact on the other processes is the data capture component, i.e. intra-oral scanners. This literature review discusses the principles and clinical use of intra-oral scanners in dentistry based on recent publications of the past 5 years using the PubMed and Google Scholar databases.