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J Menopausal Med. 2018 Apr;24(1):56-61. English. Meta-Analysis. https://doi.org/10.6118/jmm.2018.24.1.56
Khadivzadeh T , Najafi MN , Ghazanfarpour M , Irani M , Dizavandi FR , Shariati K .
Evidence-Based Care Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. masoumeh.ghazanfarpour@yahoo.com
Department of Community Medicine, Imam Reza Clinical Research Units, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Midwifery and Reproductive Health, Nursing and Midwifery School, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Community Health and Psychiatric Nursing, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Medical Education, Mashhad University of Medical Sciences, Mashhad, Iran.
Abstract

Objectives

The aim of the present systematic review and meta-analysis is the exploration of the potential evidence of the effectiveness of aromatherapy products on the sexual function of menopausal women.

Methods

From inception to December 2017, the search process was performed using the MEDLINE and Scopus databases and the Cochrane Library regarding the trials on the effectiveness of herbal-medicine aromatherapy on the sexual function of menopausal women.

Results

Three of the trials comprise suitable data for inclusion in the meta-analysis. According to the meta-analysis, it is possible to improve the standardized mean difference (SMD) of the sexual desire up to 0.56 in the aromatherapy group compared with the control group (SMD = 0.56; P < 0.001; heterogeneity; I² = 42%; P = 0.141). According to one of the trials, the serum-estrogen level of two different doses did not change in the neroli oil inhalation group compared with the almond-oil group.

Conclusions

Both aromatherapy with neroli oil or lavender (monopreparation) and combined-oil aromatherapy with lavender, fennel, geranium, and rose significantly improved human sexual function; however, a significant change of the serum-estrogen level was not detected. The findings of the present review should be presented cautiously because of the corresponding limitations such as the lack of a standardized tool, the lack of intention-to-treat reporting, the low study amount, and the short-term follow-up.

Copyright © 2019. Korean Association of Medical Journal Editors.