Endometrial biopsy can be widely used to evaluate women at high risk for endometrial cancer and to follow women on hormone replacement therapy or endometrial dating. Trsditional biopsy methods may produce enough pain to lower patient aeeeptance and differences in cost or simplieity. The Pipelle is a new disposable plastic endometrial suetion curette that provides a histologic biopsy, Recent several publications have suggested that use of the Pipelle curette is a safe and effective method by which to obtain samples of endornetriai tissue. This study compare the performance of the Pipelle curette to that of the D&C, a widely accepted biopsy technique. Pipelle curettage was perfotmed just prior to D&C on 71 patients. Both technique provided same results in 51 cases(72%). More distinctive results were obtained in 14 cases of D&C(20%). Meanwhile, the result of cases of Pipelle cureite were even more distinctive comparing to D&C. It is very remarkable fact that there were no differences in pathologic findings of five cases of cancer between and Piyelle curette. All the patients did not require any anesthesia dunng Pipelle curettage, Sixty-nine of the seventy-one patients with Fipelle biopsy did riet comp1ain any pain and two patients state4 only mild pain during the proeedure. These results suggest that Pipelle is as effective as the D&C in diagnosing endometrial bistolgy and sureior to D&C inview of the cost and pain.