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Kidney Res Clin Pract. 2016 Dec;35(4):245-251. English. Original Article. https://doi.org/10.1016/j.krcp.2016.08.002
Lee S , Kim H , Kim KH , Hann HJ , Ahn HS , Kim SJ , Kang DH , Choi KB , Ryu DR .
Department of Internal Medicine, School of Medicine, Ewha Womans University, Seoul, Korea. drryu@ewha.ac.kr
Department of Internal Medicine, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul, Korea.
Department of Public Health, Graduate School, Korea University, Seoul, Korea.
Ewha Medical Research Institute, School of Medicine, Ewha Womans University, Seoul, Korea.
Department of Preventive Medicine, College of Medicine, Korea University, Seoul, Korea.
Abstract

BACKGROUND: Technique failure is an important issue for peritoneal dialysis (PD) patients. In this study, we aimed to analyze technique failure rate in detail and to determine the predictors for technique failure in Korea. METHODS: We identified all patients who had started dialysis between January 1, 2005, and December 31, 2008, in Korea, using the Korean Health Insurance Review and Assessment Service database. A total of 7,614 PD patients were included, and the median follow-up was 24.9 months. RESULTS: The crude incidence rates of technique failure in PD patients were 54.1 per 1,000 patient-years. The cumulative 1-, 2-, and 3-year technique failure rates of PD patients were 4.9%, 10.3%, and 15.6%, respectively. However, those technique failure rates by Kaplan–Meier analysis were overestimated compared with the values by competing risks analysis, and the differences increased with the follow-up period. In multivariate analyses, diabetes mellitus and Medical Aid as a crude reflection of low socioeconomic status were independent risk factors in both the Cox proportional hazard model and Fine and Gray subdistribution model. In addition, cancer was independently associated with a lower risk of technique failure in the Fine and Gray model. CONCLUSION: Technique failure was a major concern in patients initiating PD in Korea, especially in diabetic patients and Medical Aid beneficiaries. The results of our study offer a basis for risk stratification for technique failure.

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