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Imaging Sci Dent. 2015 Mar;45(1):7-13. English. Original Article. https://doi.org/10.5624/isd.2015.45.1.7
Kang SW , Lee WJ , Choi SC , Lee SS , Heo MS , Huh KH , Kim TI , Yi WJ .
Interdisciplinary Program in Radiation, Applied Life Science Major, College of Medicine, BK21, and Dental Research Institute, Seoul National University, Korea.
Department of Oral and Maxillofacial Radiology, BK21, and Dental Research Institute, School of Dentistry, Seoul National University, Korea. wjyi@snu.ac.kr
Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University, Korea. periopf@snu.ac.kr
Abstract

PURPOSE: We have developed a new method of segmenting the areas of absorbable implants and bone using region-based segmentation of micro-computed tomography (micro-CT) images, which allowed us to quantify volumetric bone-implant contact (VBIC) and volumetric absorption (VA). MATERIALS AND METHODS: The simple threshold technique generally used in micro-CT analysis cannot be used to segment the areas of absorbable implants and bone. Instead, a region-based segmentation method, a region-labeling method, and subsequent morphological operations were successively applied to micro-CT images. The three-dimensional VBIC and VA of the absorbable implant were then calculated over the entire volume of the implant. Two-dimensional (2D) bone-implant contact (BIC) and bone area (BA) were also measured based on the conventional histomorphometric method. RESULTS: VA and VBIC increased significantly with as the healing period increased (p<0.05). VBIC values were significantly correlated with VA values (p<0.05) and with 2D BIC values (p<0.05). CONCLUSION: It is possible to quantify VBIC and VA for absorbable implants using micro-CT analysis using a region-based segmentation method.

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