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Imaging Sci Dent. 2012 Dec;42(4):225-229. English. Original Article.
Sutthiprapaporn P , Tanimoto K , Nakamoto T , Kongsomboon S , Limmonthol S , Pisek P , Keinprasit C .
Department of Oral Diagnosis, Khon Kaen University, Khon Kaen, Thailand.
Department of Oral and Maxillofacial Radiology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.
Department of Oral and Maxillofacial Surgery, Khon Kaen University, Khon Kaen, Thailand.
Department of Orthodontics, Khon Kaen University, Khon Kaen, Thailand.

PURPOSE: This study aimed to evaluate the trabecular bone changes after alveolar bone grafting in unilateral cleft lip and palate (UCLP) patients using a computer-aided diagnosis (CAD) system. MATERIALS AND METHODS: The occlusal radiographs taken from 50 UCLP patients were surveyed retrospectively. The images were categorized as: 50 images in group 0 (before bone grafting), 33 images in group 1 (one month after bone grafting), 24 images in group 2 (2-4 months after bone grafting), 15 images in group 3 (5-7 months after bone grafting), and 21 images in group 4 (8 or more months after bone grafting). Each image was grouped as either "non-cleft side" or "cleft side". The CAD system was used five times for each side to calculate the pixel area based on the mathematical morphology. Significant differences were found using a Wilcoxon signed ranks test or paired samples t test. RESULTS: The pixel area showed a significant difference between the "non-cleft side" and "cleft side" in group 0 (404.27+/-103.72/117.73+/-92.25; p=0.00), group 1 (434.29+/-86.70/388.31+/-109.51; p=0.01), and group 4 (430.98+/-98.11/366.71+/-154.59; p=0.02). No significant differences were found in group 2 (423.57+/-98.12/383.47+/-135.88; p=0.06) or group 3 (433.02+/-116.07/384.16+/-146.55; p=0.19). CONCLUSION: Based on the design of this study, alveolar bone grafting was similar to normal bone within 2-7 months postoperatively.

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