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J Korean Neurol Assoc. 2017 Aug;35(3):162-165. Korean. Case Report.
Choi N , Lee JY , Sunwoo JS , Kwon KI , Roh H , Ahn MY , Lee KB .
Department of Neurology, Soonchunhyang University Seoul Hospital, Seoul, Korea.

A 61-year-old woman with chronic kidney disease presented with general weakness and a confused mentality. Two days before admission she had been diagnosed as Bell's palsy at an outpatient clinic, and started to take oral prednisolone and acyclovir. A blood test at admission revealed hyponatremia (128 mmol/L). After withdrawing acyclovir, her plasma sodium levels began to increase, returning to normal 2 weeks later. This case could provide further evidence for a causal relationship between acyclovir and hyponatremia.

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