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J Korean Neurol Assoc. 2007 Feb;25(1):112-114. Korean. Case Report.
Park J , Oh KW , Koh SH , Kim HT , Kim SH , Kim J , Kim MH .
Department of Neurology, College of Medicine, Hanyang University, Korea.

Neurological complications associated with Crohn's disease are infrequent and optic neuritis is extremely rare. We report a 20-year-old man showing optic neuritis and Wernicke's encephalopathy as complications of Crohn's disease. We suggest that nutritional deficiency caused Wernicke's encephalopathy and the immunologic abnormality of Crohn's disease induced the complication of optic neuritis. This patient is the first reported case showing optic neuritis and Wernicke's encephalopathy simultaneously as neurological complications of Crohn's disease in Korea.

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