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J Korean Neurol Assoc. 2006 Dec;24(6):581-584. Korean. Case Report.
Kwon KY , Lee DK , Lee KH , Cho KH , Lee E , Chung SJ .
Department of Neurology, University of Ulsan College of Medicine, Seoul, Korea.

Metronidazole is an antimicrobial agent widely used for the treatment of trichomoniasis, giardiasis, amebiasis, and anaerobic bacterial infections. It has been reported that metronidazole-induced neurotoxicity is associated with responsible lesions on brain MRI. We report 2 patients with metronidazole-induced neurotoxicity, who had no responsible lesions on brain MRI for their neurological deficits. The pathogenic mechanisms are discussed.

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