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J Korean Neurol Assoc. 2006 Dec;24(6):535-543. Korean. Multicenter Study.
Yu KH , Bae HJ , Kwon SU , Kang DW , Hong KS , Lee YS , Rha JH , Koo JS , Kim JS , Kim JH , Lee JH , Cho SJ , Hwang SH , Jung S , Han MK , Cho KH , Kim BC , Shin DJ , Chang DI , Park JH , Kim EG , Jung DS , Ahn MY , Lee DH , Park KW , Kim YJ , Lee KY , Heo JH , Kim SH , Lee KH , Chung CS , Cha JK , Lee JH , Uhm KY , Lee BC , Roh JK .
Department of Neurology, Hallym University College of Medicine, Korea. ssbrain@hallym.ac.kr
Department of Neurology, Eulji University School of Medicine, Korea.
Department of Neurology, University of Ulsan College of Medicine, Korea.
Department of Neurology, Inje University College of Medicine, Korea.
Department of Neurology, Seoul National University Boramae Hospital, Korea.
Department of Neurology, Inha University College of Medicine, Korea.
Department of Neurology, Seoul National University College of Medicine, Korea.
Department of Neurology, Chonnam National University Medical School, Korea.
Department of Neurology, Gachon Medical School, Korea.
Department of Neurology, Kyunghee University College of Medicine, Korea.
Department of Neurology, Pusan National University College of Medicine, Korea.
Department of Neurology, Soonchunhyang University College of Medicine, Korea.
Department of Neurology, Korea University College of Medicine, Korea.
Department of Neurology, Ewha Womans University College of Medicine, Korea.
Department of Neurology, Yonsei University College of Medicine, Korea.
Department of Neurology, Hanyang University College of Medicine, Korea.
Department of Neurology, Sungkyunkwan University School of Medicine, Korea.
Department of Neurology, Dong-A University College of Medicine, Korea.
Department of Neurology, National Health Insurance Corporation Ilsan Hospital, Korea.
Department of Neurology, KwangMyungSungAe Hospital, Korea.
Department of Neurology, Bundang Seoul National University Hospital, Korea.
Abstract

BACKGROUND: Although several hospital-based stroke studies were published, there has not been any reliable data representing the clinical characteristics of stroke in Korea. We analyzed the clinical characteristics of patients with ischemic stroke registered in the Korean Stroke Registry (KSR), which is the largest prospective hospital-based nation-wide stroke registry in Korea. METHODS: The KSR provided standardized protocols for collecting data, which includes the data of demographics, subtypes of stroke, risk factors, and neurological outcome at discharge. The brain imaging studies, including CT or MRI, were performed in all cases. RESULTS: KSR registered 10,811 patients of acute ischemic stroke between Nov. 2002 and Jun. 2004. The large-artery atherosclerosis was the most common subtype (37.3%), followed by small vessel occlusion (30.8%). Hypertension (65.4%) was the most common risk factor, followed by smoking (34.5%) and diabetes (28.3%). Although most of the hypertensive and diabetic patients had been diagnosed before the stroke, less than 45.4% and 32.5% of them were under regular control. The steno-occlusive lesion of extracranial carotid artery was only 29.3% and the ratio of intra- to extracranial artery disease was more than 2 in KSR. Only 20.5% of patients were admitted within 3 hours after stroke onset and 2.1% were treated with intravenous thrombolysis. In-hospital case-fatality was 5.2%, which is relatively comparable to those of previous studies. CONCLUSIONS: The KSR provided informative data in understanding the clinical characteristics of ischemic stroke in Korea. Further analysis of KSR will facilitate clinical trials and development of guidelines for the management of stroke patients.

Copyright © 2019. Korean Association of Medical Journal Editors.