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J Korean Neurol Assoc. 2005 Dec;23(6):836-839. Korean. Case Report.
Kim HJ , Hong S , Han JK , Kim BJ , Park KW , Lee DH , Oh K , Sim WJ , Park SS , Shin SY .
Department of Neurology, Korea University College of Medicine, Seoul, Korea. dystonia@medimail.co.kr
Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Abstract

Obesity-Hypoventilation syndrome (OHS) is characterized by morbid obesity, hypoxia, and hypercapnea during wakefulness without parechymal lung disease or severe obstructive sleep apnea. A woman was admitted because of mental deterioration and diagnosed as OHS on the basis of obesity and hypoventilation, while awake, after ruling out other causes. By bilevel positive airway pressure (BiPAP) therapy, hypercapnea and hypoxia were resolved. We report that BiPAP can be an effective treatment for severe hypercapnea and hypoxia in OHS, which obviate the need for invasive endotracheal intubation.

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