The ptosis secondary to cerebral hemispheric lesion (cerebral ptosis) is unusual and has not been well documented. Although the precise anatomical localization and clinical course of cerebral ptosis were not clear, there have been a few clinical and electrophysiologlcal reports that right hemisphere had its functional asymmetry or dominancy in the cortical control of eyelid movement. We present 4 patients of cerebral ptosis with acute onset of cerebral infarction in right middle cerebral artery territory. All of them are right-handed and presented acute onset of left hemiparesis and bilateral ptosis, but have no signs of involvement of oculomotor or sympathetic nerve pathway. In conclusion, the blepharoptosis could be caused by hemispheric lesion per se and be a sign of right hemispheric lesion rather than that of left one.