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J Pathol Transl Med. 2015 Mar;49(2):129-135. English. Original Article. https://doi.org/10.4132/jptm.2015.01.28
Misra RK , Mitra S , Jain RK , Vahikar S , Bundela A , Misra P .
Department of Pathology, B.R.D. Medical College, Gorakhpur, India. shaila.prasad14@yahoo.co.in
Department of Radiology, B.R.D. Medical College, Gorakhpur, India.
Apollo Hospital, New Delhi, India.
Abstract

BACKGROUND: Although using fine needle cytology with aspiration (FNC-A) for establishing diagnoses in the retroperitoneal region has shown promise, there is scant literature supporting a role of non-aspiration cytology (FNC-NA) for this region. We assessed the accuracy and reliability of FNC-A and FNC-NA as tools for preoperative diagnosis of retroperitoneal masses and compared the results of both techniques with each other and with histopathology. METHODS: Fifty-seven patients with retroperitoneal masses were subjected to FNC-A and FNC-NA. Smears were stained with May-Grunwald Giemsa and hematoxylin and eosin stain. An individual slide was objectively analysed using a point scoring system to enable comparison between FNC-A and FNC-NA. RESULTS: By FNC-A, 91.7% accuracy was obtained in cases of retroperitoneal lymph node lesions followed by renal masses (83.3%). The diagnostic accuracy of other sites by FNC-A varied from 75.0%-81.9%. By FNC-NA, 93.4% diagnostically accurate results were obtained in the kidney, followed by 75.0% in adrenal masses. The diagnostic accuracy of other sites by FNC-NA varied from 66.7%-72.8%. CONCLUSIONS: Although both techniques have their own advantages and disadvantages, FNC-NA may be a more efficient adjuvant method of sampling in retroperitoneal lesions.

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