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J Korean Soc Radiol. 2018 Aug;79(2):57-62. Korean. Original Article. https://doi.org/10.3348/jksr.2018.79.2.57
Yang GE , Han H , Hong JY , Ohk TG .
Department of Radiology, Kangwon National University Hospital, Chuncheon, Korea. hanheon@kangwon.ac.kr
Department of Medicine, Hallym University Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.
Department of Emergency Medicine, Kangwon National University Hospital, Chuncheon, Korea.
Abstract

Purpose

To compare initial CT findings of non-tuberculous mycobacteria (NTM) pulmonary infection between stable and progressed groups and determine whether they could be used to predict disease prognosis and treatment response.

Materials and Methods

From July 2006 to October 2013, 71 patients with NTM infection were retrospectively reviewed. Lung lesion pattern of CT finding, specific species, disease duration, and follow-up period were analyzed. These patients were classified into NTM stable (n = 46) and progressed (n = 25) groups.

Results

The most common CT findings of NTM infection were small nodules (n = 71, 100%) and bronchiectasis (n = 67, 94%). Large consolidation (> 2 cm, n = 34, 48%) and involvement of more than four lobes (n = 49, 69%) were also commonly observed. According to disease prognosis, large consolidation (n = 18, 72%, p = 0.003), cavitary lesion (n = 17, p = 0.002), and involvement of four or more lobes (n = 21, p = 0.044) on CT were significantly more frequent in disease progressed group than that in the stable group.

Conclusion

Among common CT findings of NTM disease, some CT findings such as large consolidation, cavitary lesion, and disease extent are good predictors of response to treatment in NTM pulmonary disease.

Copyright © 2019. Korean Association of Medical Journal Editors.