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Diabetes Metab J. 2012 Dec;36(6):433-442. English. Original Article. https://doi.org/10.4093/dmj.2012.36.6.433
Lou QL , Ouyang XJ , Gu LB , Mo YZ , Ma R , Nan J , Kong A , So WY , Ko G , Chan J , Chow CC , Bian RW .
Diabetes Care and Research Center, Jiangsu Province Institute of Geriatrics, Nanjing, China. bianrw@126.com
Department of Endocrinology and Metabolism, Jiangsu Province Institute of Geriatrics, Nanjing, China.
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.
Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China.
Abstract

BACKGROUND: To determine the frequency of chronic kidney disease (CKD) and its associated risk factors in Chinese type 2 diabetic patients, we conducted a cross-sectional study in Nanjing, China, in the period between January 2008 and December 2009. METHODS: Patients with type 2 diabetes under the care by Jiangsu Province Official Hospital, Nanjing, China were invited for assessment. CKD was defined as the presence of albuminuria or estimated glomerular filtration rate <60 mL/min/1.73 m2. Albuminuria was defined as urinary albumin-to-creatinine ratio > or =30 mg/g. RESULTS: We recruited 1,521 urban Chinese patients with type 2 diabetes (mean age, 63.9+/-12.0 years). The frequency of CKD and albuminuria was 31.0% and 28.9%, respectively. After adjusted by age and sex, hypertension, anemia and duration of diabetes were significantly associated with CKD with odds ratio (95% confidence interval) being 1.93 (1.28 to 2.93), 1.70 (1.09 to 2.64), and 1.03 (1.00 to 1.06), respectively. CONCLUSION: In conclusion, CKD was common in the urban Nanjing Chinese with type 2 diabetes. Strategies to prevent or delay progression of kidney disease in diabetes should be carried out at the early disease course of type 2 diabetes.

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