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Korean J Clin Neurophysiol. 2014 Jun;16(1):27-31. Korean. Case Report.
Kim DH , Oh SY .
Department of Neurology, Chonbuk National University College of Medicine, Jeonju, Korea.
Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea.

Thiamine deficiency can cause peripheral polyneuropathy and Wernicke's encephalopathy. Wernicke's encephalopathy is characterized by ataxia, ophthalmoplegia, nystagmus, and confusion, and typically presents acute and rapidly progressive course, whereas peripheral neuropathy associated with thiamine deficiency manifests chronic and slowly progressive one. However, acute and rapidly progressive axonal polyneuropathy combined with Wernicke's encephalopathy is quite rare and unusual. Here, we describe a patient with Wernicke's encephalopathy who presented with acute bilateral axonal neuropathy.

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