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Int J Thyroidol. 2018 Nov;11(2):176-181. English. Case Report.
Kang MI , Kim D .
Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea.
Department of Kinesiologic Medical Science, Graduate, Dankook University, Cheonan, Korea.

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis has been reported in Graves' disease patients treated with antithyroid drugs (ATDs), especially propylthiouracil. ATD-induced ANCA-associated vasculitis usually involved the kidneys followed by the respiratory organs and skin. The treatment of ANCA-associated vasculitis induced by ATDs is to stop ATD therapy immediately, which often leads to an overall good prognosis. We report a case of ANCA-associated vasculitis in the peripheral nerves of the lower extremities in a 66-year-old woman who was treated with methimazole (MMI) for Graves' disease. To our knowledge, this is the third case of peripheral nervous system (PNS) involvement of ATD-induced vasculitis and the first case of PNS vasculitis associated with MMI.

Copyright © 2019. Korean Association of Medical Journal Editors.