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Int J Thyroidol. 2018 Nov;11(2):172-175. Korean. Case Report. https://doi.org/10.11106/ijt.2018.11.2.172
Kim H , Kim MJ , Song YS , Cho SW .
Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea. swchomd@gmail.com
Abstract

Anti-programmed cell death-1 (PD-1) humanized monoclonal antibody inhibits PD-1 activity by binding to the PD-1 receptor on T-cells and blocking PD-1 ligands and induces immune tolerance of cancer cells. It has been widely used for various kinds of cancer treatment. However, many immune-related adverse events (irAEs) have been reported because it modulates our immune system. In this case study, we reported a case of 42-year-old woman with Hashimoto's thyroiditis who showed rapid aggravation of thyroid goiter and acute hyperventilation syndrome after treatment with PD-1 inhibitor as a neoadjuvant chemotherapy for breast cancer.

Copyright © 2019. Korean Association of Medical Journal Editors.