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Osteoporosis. 2011 Apr;9(1):46-50. English. Original Article.
Choi H , Jung MH , Ji YI , Jung H , Lee JY , Choi WJ , Kim A , Choi JS , Oh YL , Kim HY .
Department of Obstetrics and Gynecology, School of Medicine, Sanggye Paik Hospital, Inje University, Seoul, Korea.
Department of Obstetrics and Gynecology, Kyung Hee Medical Center, Kyung Hee University, Seoul, Korea.
Department of Obstetrics and Gynecology, Haeundae Paik Hospital, Inje University, Busan, Korea.
Department of Obstetrics and Gynecology, College of Medicine, Chosun University, Gwangju, Korea.
Department of Obstetrics and Gynecology, School of Medicine, Konkuk University, Seoul, Korea.
Department of Obstetrics and Gynecology, School of Medicine, Gyeongsang National University, Jinju, Korea.
Department of Obstetrics and Gynecology, College of Medicine, Wonkwang University, Gunpo, Korea.
Department of Family Medicine, Kosin University, Busan, Korea.
Department of Obstetrics and Gynecology, Kosin University, Busan, Korea. hykyale@yahoo.com
Abstract

OBJECTIVES: To investigate the spinal bone mineral density (BMD) in patients with invasive cervical cancer without bone metastases. METHODS: We measured spinal bone mineral densities by dual-photon absorptiometry in 119 patients with invasive uterine cervical cancer and compared them with measurements from 135 control women. RESULTS: When adjusted for age, mean bone mineral density in patients with uterine cervical cancer was 13.9% lower (P=0.0003) and age-matched percentiles were 9.2% lower (P=0.0003) than in control women. The deficits in bone mineral density and age-matched percentiles were confined to the uterine cervical cancer patients in their fifties. CONCLUSIONS: Our study results suggest that patients with invasive cervical cancer have a lower spinal BMD, resulting in an increased risk of osteoporosis.

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