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J Periodontal Implant Sci. 2011 Oct;41(5):242-247. English. Original Article.
Kim S , Myung WC , Lee JS , Cha JK , Jung UW , Yang HC , Lee IS , Choi SH .
Department of Prosthodontics, Yonsei University College of Dentistry, Seoul, Korea.
Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Korea.
Department of Dental Biomaterials Science and Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea.
Institute of Physics and Applied Physics, Atomic-Scale Surface Research Center, Yonsei University, Seoul, Korea.

PURPOSE: The purpose of this study was to characterize the osseointegration of the fibronectin-coated implant surface. METHODS: Sand-blasted, large-grit, acid-etched (SLA) surface implants, with or without a thin calcium phosphate and fibronectin coating, were placed in edentulous mandibles of dogs 8 weeks after extraction. All dogs were sacrificed forhistological and histomorphometric evaluation after 4- and 8-week healing periods. RESULTS: All types of implants were clinically stable without any mobility. Although the bone-to-implant contact and bone density of the SLA implants coated with calcium phosphate (CaP)/fibronectin were lower than the uncoated SLA implants, there were no significant differences between the uncoated SLA surface group and the SLA surface coated with CaP/fibronectin group. CONCLUSIONS: Within the limits of this study, SLA surfaces coated with CaP/fibronectin were shown to have comparable bone-to-implant contact and bone density to uncoated SLA surfaces.

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