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Asian Oncol Nurs. 2016 Dec;16(4):242-250. English. Original Article. https://doi.org/10.5388/aon.2016.16.4.242
Chung J , Kwon J , Kim HK , Ju G , Kim ST , Han HS .
Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea. sook3529@hanmail.net
College of Nursing, Chonbuk Research Institute of Nursing Science, Chonbuk National University, Jeonju, Korea.
Department of Psychiatry, Chungbuk National University Hospital, Cheongju, Korea.
Department of Internal Medicine, College of Medicine, Chungbuk National University, Cheongju, Korea.
Abstract

PURPOSE: The purpose of the present study was to assess factors associated with quality of life (QOL) and to determine whether anxiety and depression are predictive of QOL in patients with advanced gastrointestinal cancer at initial diagnosis and during the treatment process. METHODS: One hundred and twenty patients with gastrointestinal cancer requiring palliative chemotherapy were enrolled. RESULTS: At baseline, depression, performance status, and anxiety accounted for 55.0% (p<.001) of the variance in global health status score, depression accounted for 22.0% (p<.001) of the variance in functional scales score, and anxiety accounted for 19.0% (p<.001) of the variance in symptom scales score. At 3 months, depression, pain, and performance status accounted for 72.0% (p<.001) of the variance in global health status score, 76.0% (p<.001) of the variance in functional scales score, and 74.0% (p<.001) of the variance in symptom scales score. CONCLUSION: Anxiety and depression were significant predictive factors of QOL in patients with advanced gastrointestinal cancer. Depression and performance status were significant predictive factors of QOL at both baseline and 3 months, and anxiety and pain were significant predictive factors of QOL at baseline and 3 months, respectively.

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