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J Korean Soc Biol Psychiatry. 1998 Nov;5(2):210-214. Korean. Original Article.
Song ES , Chai YG , Yang BH , Park KK , Oh DY , Kim GS , Lee YS , An ES , Kim JW , Choi IG .
Abstract

An association study with Korean schizophrenic patients(N=84) and normal controls(N=87) was performed to find the relationship between catechol-o-methyltransferase(COMT) gene polymorphism and schizophrenia using polymerase chain reaction-restriction fragment length polymorphism. When we compared the allele and genotype frequencies of Bg/I COMT gene polymorphism in schizophrenics and normal controls, there was no significant difference between two groups. Our results do not support an association between the Bg/I polymorphism of COMT gene and schizophrenia.

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