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J Gastric Cancer. 2015 Dec;15(4):256-261. English. Meta-Analysis. https://doi.org/10.5230/jgc.2015.15.4.256
Fallahzadeh H , Jalali A , Momayyezi M , Bazm S .
Research Center of Prevention and Epidemiology of Non-Communicable Disease, Shahid Sadoughi University of Medical Sciences, Iran.
Department of Epidemiology, Faculty of Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. namjo14@yahoo.com
Department of Health Education, Faculty of Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Abstract

PURPOSE: Gastric cancer is the third leading cause of cancer-related mortality, with the incidence and mortality being higher in men than in women. Various studies have shown that eating carrots may play a major role in the prevention of gastric cancer. We conducted a meta-analysis to determine the relationship between carrot consumption and gastric cancer. MATERIALS AND METHODS: We searched multiple databases including PubMed, Cochrane Library, Scopus, ScienceDirect, and Persian databases like Scientific Information Database (SID) and IranMedx. The following search terms were used: stomach or gastric, neoplasm or cancer, carcinoma or tumor, and carrot. Statistical analyses were performed using Comprehensive Meta Analysis/2.0 software. RESULTS: We retrieved 81 articles by searching the databases. After considering the inclusion and exclusion criteria, 5 articles were included in this study. The odds ratio (OR) obtained by fixed effects model showed that a 26% reduction in the risk of gastric cancer has been associated with the consumption of carrots) OR=0.74; 95% confidence interval=0.68~0.81; P<0.0001). According to funnel graph, the results showed that the possibility of a publication bias does not exist in this study. CONCLUSIONS: The findings of this study showed an inverse relationship between the consumption of carrots and the risk of gastric cancer.

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