PURPOSE: The main purposes of this descriptive survey study were to describe parenting stress and needs of mothers of children with atopic dermatitis. METHOD: Data were collected from 111 mothers of children under 6 year-old with atopic dermatitis registered at one university affiliated medical center in Seoul. The instruments used for this study were a self-report questionnaire, Parenting Stress Index (PSI) Short Form by Abidin, and an open question to identify nursing needs. Descriptive analysis, Pearson correlation and contents analyses were done. RESULT: The mean score for parenting stress was 77.25 (range: 12-60), for parent domain 31.50 (range: 12-60), Parent-Child domain 21.02 (range: 11-55) and child domain was 24.72 (range: 11-51). There was a significant positive relationship between parenting stress and severity of symptom (r=0.192, p<.005). The maternal stressors included extra housework related to symptom management, treatment related to atopic dermatitis, personality and behavior of child, and financial problems. CONCLUSION: the mothers of children with atopic dermatitis have high parenting stress from various stressors and needs. It is recommended that nursing interventions should include stress management and take into consideration the educational needs of mothers.