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Korean J Adult Nurs. 2018 Oct;30(5):493-503. Korean. Original Article.
Jung EY , Hwang SK .
RN, Respiratory Center, Pusan National University Hospital, Busan, Korea.
Professor, College of Nursing, Pusan National University, Yangsan, Korea.


This study aimed to explore medication adherence and its related factors, stigma, self-efficacy, and sense of coherence in patients with tuberculosis.


A cross-sectional survey was conducted with a convenience sample of 130 adult outpatients with tuberculosis at a university hospital in Busan during from May 1 to August 21, 2017. The data were collected using structured questionnaires comprising research instruments measuring medication adherence, stigma, self-efficacy, and sense of coherence and face-to-face interviews and medical records for treatment delays and participant characteristics. The SPSS/WIN 22.0 program for descriptive statistics, Pearson's correlation coefficients and stepwise multiple regression were used to analyze the data.


The mean score for medication adherence was 4.86±1.48. The factors related to medication adherence in adult outpatients with tuberculosis were stigma (β=−.23, p=.004), self-efficacy (β=.20, p=.036), perceived family support (β=.19, p=.012), and alcohol (β=−.19, p=.021), which explained 38.9% of the variance in medication adherence.


The study results suggest that a nursing intervention must be designed to reduce stigma, improve self-efficacy, promote family support, and stop alcohol consumption in order to enhance the medication adherence in adult patients with tuberculosis. Efforts need to educate and encourage tuberculosis patients to adhere strictly to their drugs and conduct various campaigns against the negative perception of tuberculosis.

Copyright © 2019. Korean Association of Medical Journal Editors.