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Int Neurourol J. 2018 Sep;22(3):192-199. English. Original Article.
Cho OH , Yoo YS , Kim JC , Park RH , Hwang KH .
Department of Nursing, College of Nursing and Health, Kongju National University, Gongju, Korea.
College of Nursing, The Catholic University of Korea, Seoul, Korea.
Department of Urology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea.
Department of Nursing, Seoul St. Mary's Hospital, Seoul, Korea.
Department of Nursing, Suwon Science College, Hwaseong, Korea.


This study aimed to investigate the severity of lower urinary tract symptoms (LUTS) and to identify factors that influenced LUTS in advanced cancer patients with chemotherapy-induced peripheral neuropathy (CIPN).


This cross-sectional study included a total of 158 advanced cancer patients with CIPN. A structured questionnaire including the International Prostate Symptom Score and the Functional Assessment of Cancer Therapy/Gynecology Oncology Group/Neurotoxicity scale was used. Data were analyzed using the Pearson correlation coefficient and multiple regression analysis.


Nocturia was the most prevalent LUTS. A positive relationship was found between CIPN symptoms and LUTS. The duration of cancer diagnosis and the severity of CIPN were key factors that influenced LUTS.


The severity of CIPN symptoms was the most important predictor of LUTS. Nurses' care for advanced cancer patients should incorporate a comprehensive health assessment, which includes a history of treatment and physical neuropathic symptoms, for any patient complaining of CIPN symptoms.

Copyright © 2019. Korean Association of Medical Journal Editors.