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Infect Chemother. 2017 Dec;49(4):268-274. English. Original Article. https://doi.org/10.3947/ic.2017.49.4.268
Kim YC , Ahn JY , Kim JM , Kim YJ , Park DW , Yoon YK , Song JY , Kim SW , Lee JS , Choi BY , Choi YS , Choi JY , Han MG , Kang C , Choi JY .
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. seran@yuhs.ac
Division of Infectious Disease, Department of Internal Medicine, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
Division of Infectious Disease, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.
Department of Internal Medicine, Inha University School of Medicine, Incheon, Korea.
Department of Preventive Medicine, Hanyang University College of Medicine, Seoul, Korea.
Institute for Health and Society, Hanyang University, Seoul, Korea.
Korea Centers for Disease Control and Prevention, Cheongju, Korea.
Abstract

Background

Despite declines in mortality and morbidity rates of patients with human immunodeficiency virus (HIV) infection as the result of highly active antiretroviral therapy, liver diseases due to chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are a leading cause of death among HIV-infected patients. However, HIV and HBV or HCV coinfection is still poorly documented, and more information is needed to better understand the characteristics of HIV-infected patients in Korea.

Materials and Methods

A cross-sectional study was performed to investigate clinical characteristics and prevalence of HBV and HCV infection in HIV patients enrolled in the Korea HIV/acquired immune deficiency syndrome (AIDS) cohort study from 17 institutions between December 2006 and July 2013.

Results

Among the 1,218 HIV-infected participants, 541 were included in this study. The prevalence of HBV-HIV and HCV-HIV coinfection was 5.0% (27/541) and 1.7% (9/541), respectively. There was no patient who was positive for both HBs antigen and HCV antibody. In multivariate logistic regression analysis, HBV unvaccinated status was a significant risk factor for HBV-HIV coinfection (odds ratio = 4.95, 95% confidence interval = 1.43–17.13).

Conclusions

HBV and HCV infection was more common in HIV-infected persons enrolled in the Korean HIV/AIDS cohort, than in the general population in Korea.

Copyright © 2019. Korean Association of Medical Journal Editors.