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Korean J Hematol. 2001 Nov;36(4):355-358. Korean. Case Report.
Park JA , Kim KW , Park SY , Park HC , Yoon CH , Kim HJ , Lee EH , Lee HK , Kay CS .
Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Department of Therapeutic Radiology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Abstract

Epstein-Barr virus (EBV), a human lymphotropic herpesvirus, is presently the best known viral contributor to the development of human lymphomas and transforms normal resting B cells into immunoblasts. Especially a positive correlation has been found between the EBV- associated lymphadenopathy and the later development of EBV-carrying lymphoma in patients with acquired immune deficiency syndrome. Anaplastic large cell lymphoma(ALCL) is a clinicopathologically distinct category of non-Hodgkin's lymphoma (NHL) and classified as T-/null-cell type lymphomas in the revised European-American Classification of lymphoid neoplasms. We report a patient with EBV- associated B-cell ALCL and HIV positive. EBV-associated ALCL in HIV-positive patient usually has B-cell phenotype, so this lymphoma should be distinguished from the classical ALCL as were defined by the revised European-American Classification of lymphoid neoplasms.

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