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Korean J Hematol. 2001 Nov;36(4):351-354. Korean. Case Report.
Oh HM , Whang NC , Lim SJ , Kim JH , Kim YK , Kim SY , Kim YJ , Cho MK , Lee GJ .
Department of Internal Medicine, National Police Hospital, Seoul, Korea.

Hereditary factor VII deficiency is a rare disorder transmitted by autosomal recessive pattern and its clinical feature is extremely variable. Recently we have experienced a case who was performed herniorrhaphy without any cryoprecipitate or fresh frozen plasma replacement therapy. A 21-year-old patient who had undergone intermittent nasal bleeding was noted for prolonged prothrombin time(INR of 1.5). The level of the factor VII of the patient was decreased at 22% of the normal activity. His parents had normal level of factor VII activity. Both his sister and brother had decreased level of factor VII at 41% and 24% respectively. Herniorrhaphy was performed without factor replacement therapy and there was no visible postoperative bleeding. We report here a case of factor VII deficiency performed an operation successfully without any replacement therapy.

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