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J Korean Assoc Oral Maxillofac Surg. 2006 Jun;32(3):189-199. Korean. Original Article.
Ahn KM , Lee JH , Lee UL , Lee JH , Lee JW , Kim SP , Yang EK , Kim KH .
Department of Oral and Maxillofacial Surgery, College of Medicine, Ulsan University, Korea.
Department of Oral and Maxillofacial Surgery, College of Dentistry, Seoul National University, Korea. leejongh@plaza.snu.ac.kr
Bioland Incorporation, Korea.
Abstract

<0.05). 4. Histologic examination revealed that AM protected leukocyte infiltration and epithelial migration was nearly completed at 4 weeks. Terudermis(R) group showed mild neutrophil infiltration until 2 weeks and completion of epithelization at 4 weeks. Control group showed massive leukocyte infiltration until 4 weeks. 5. Microvessels were increased sharply at 1 week and control group at 1 and 4 week showed significant differences with Terudermis(R) group of same interval(p<0.05) but no differences were found with AM group(p<0.05). CONCLUSION: EGF and EGF-R were well preserved in freeze-dried AM. AM attached to collagen acted as excellent biologic dressing which had similar effect with Terudermis(R). AM showed anti-inflammatory action and healing was completed at 4 weeks after full-thickness skin defect.

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