BACKGROUND: This research was carried out for the distribution of the risk factors and groups of coronary artery disease (CAD) in office female workers. The purpose is selection for preferred subjects and developing basic data for the CAD prevention program. METHODS: From November to December in 1995, we examined CAD risk factors, general characteristics, physical activity, diet intake and cholesterol level. Then we selected the CAD risk groups by NCEP II 1993. For the statistic analysis, used chi-square test and t-test. RESULT: There was current cigarette smoking 2 (0.3%), hypertension 37 (4.8%), diabetes mellitus 2 (0.3%) and low HDL-C 100 (12.9%). CAD negative risk factor, high HDL-C was 128 (16.5%). The number of subjects with no risk factor was 647 (83.5%), that of 1 was 121 (15.5%), and that of over 2 was 7 (1.0%), who were all over 40 and clustered. The number of normal population was 584 (75.6%) and CAD risk groups was 188 (24.4%)-severe 37 (4.8%), moderate 22 (2.9%), and mild 129 (16.7%) - according to NCEP II 1993. Seven day physical activity was 39.2 MET. Low physical activity group members whose activity time was below 30 minutes per day was 79.2%; 79.7% (458/575) for normal and 77.7% (143/184) for CAD risk group. The subjects who had no hard activity was 44% of them. High fat intake group that the energy absorption proportion over the total energy was over 25% was 2.1% (14/652) for normal and 0.9% (6/652) for CAD risk group. The body mass index (BMI) was 22.2 kg/m2 on the average and showed the remarkable increase in older (P<0.01). CONCLUSION: Those who had more than 2 CAD risk factors were all over 40 years. The ratio of CAD risk groups over 45 increased meaningly. The BMI in CAD risk groups increased meaningly, and physical inactivity did too. For this subjects, CAD prevention program was severe, moderate and mild risk group in priority and should be focused on prevention, control of obesity, and increase of physical activity.