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J Korean Soc Echocardiogr. 1996 Dec;4(2):115-122. Korean. Original Article.
Kim KJ , Kang HS , Choue CW , Kim KS , Kim MS , Song JS , Bae JH .
Division of Cardiology, Department of Internal Medicine, College of Medicine, Kyunghee University, Seoul, Korea.


Myocardial dysfunction after thrombolytic therapy in patients with acute myocardial infarction may be reversible. Early after myocardial infarction, both reversible and irreversble injury may be manifested by regional wall motion abnormalities. Improved wall motion during low dose dobutamine infusion (dobutamine reponsive wall motion) may identify reversible injured segments.


To determine the dobutamine responsive wall motion and reversibility of MIBI heart SPECT, twenty-eight patients with acute myocardial infarction were evaluated.


1) Reponse and nonresponse rate of low dose dobutamine stress echocardiography were 25%(7/28) and 75%(21/28). 2) Reversible and fixed perfusion rate of MIBI heart SPECT were 54%(15/28) and 46%(13/28). 3) Concordance rate between low dose dobutamine stress echoacardiography and MIBI heart SPECT was 50%(14/28).


These results suggest that low dose dobutamine stress echocardiography may be useful diagnostic method for the detection of viability in patients with acute myocardial infarction.

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