Journal Browser Advanced Search Help
Journal Browser Advanced search HELP
Korean Circ J. 2018 Nov;48(11):989-999. English. Original Article. https://doi.org/10.4070/kcj.2017.0387
Kwon SW , Park SD , Moon J , Oh PC , Jang HJ , Park HW , Kim TH , Lee K , Suh J , Kang W .
Department of Cardiology, Inha University Hospital, Incheon, Korea. denki1@inha.ac.kr
Department of Cardiology, Gachon University Gil Medical Center, Incheon, Korea.
Department of Cardiology, Sejong General Hospital, Bucheon, Korea.
Department of Cardiology, Soonchunhyang University Bucheon Hospital, Bucheon, Korea. denki1@inha.ac.kr
Abstract

Background and Objectives

We aimed to compare outcomes of complete revascularization (CR) versus culprit-only revascularization for ST-segment elevation myocardial infarction (STEMI) and multivessel disease (MVD) in the 2(nd) generation drug-eluting stent (DES) era.

Methods

From 2009 to 2014, patients with STEMI and MVD, who underwent primary percutaneous coronary intervention (PCI) using a 2(nd) generation DES for culprit lesions were enrolled. CR was defined as PCI for a non-infarct-related artery during the index admission. Major adverse cardiovascular event (MACE) was defined as cardiovascular (CV) death, non-fatal myocardial infarction, target lesion revascularization, or heart failure during the follow-up year.

Results

In total, 705 MVD patients were suitable for the analysis, of whom 286 (41%) underwent culprit-only PCI and 419 (59%) underwent CR during the index admission. The incidence of MACE was 11.5% in the CR group versus 18.5% in the culprit-only group (hazard ratio [HR], 0.56; 95% confidence interval [CI], 0.37–0.86; p < 0.01; adjusted HR, 0.64; 95% CI, 0.40–0.99; p=0.04). The CR group revealed a significantly lower incidence of CV death (7.2% vs. 12.9%; HR, 0.51; 95% CI, 0.31–0.86; p=0.01 and adjusted HR, 0.57; 95% CI; 0.32–0.97; p=0.03, respectively).

Conclusions

CR was associated with better outcomes including reductions in MACE and CV death at 1 year of follow-up compared with culprit-only PCI in the 2(nd) generation DES era.

Copyright © 2019. Korean Association of Medical Journal Editors.