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Korean Circ J. 2013 Jul;43(7):504-507. English. Case Report. https://doi.org/10.4070/kcj.2013.43.7.504
Hwang JA , Yang TH , Lee JY , Koo DW , Choi IS , Cho SY , Kim MS .
Division of Cardiology, Department of Internal Medicine, Inje University College of Medicine, Cardiovascular Research Institute, Busan Paik Hospital, Busan, Korea. yangthmd@naver.com
Cardiology Division, Department of Internal Medicine, Gachon University, Incheon, Korea.
Abstract

A 65 year-old female with a history of xerostomia and xerophthalmia was presented with dyspnea on exertion (New York Heart Association class III). Echocardiography and cardiac catheterization demonstrated severe pulmonary hypertension (PH). Laboratory examinations showed positive anti-nuclear and anti-Ro/SS-A antibodies. Schirmer's test was positive and salivary gland scintigraphy revealed severely decreased tracer uptakes in both parotid and submandibular glands. By excluding other possible causes of PH during further examinations, she was diagnosed with severe PH associated with primary Sjogren's syndrome. Her dyspnea symptom was much improved with endothelin receptor antagonist and azathioprine.

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